Obese children metabolize drugs differently
The discovery will lead to a deeper study of the correlation of face to redefine the doses of drugs for pediatric patients.
Researchers at the University of Minnesota, United States, ensure that obese children metabolize drugs differently from those who have a healthy weight, according to results of a pilot study presented at the conference of the American Society of Pharmacology and Experimental Therapeutics held these days in the U.S. city of Anaheim.
In particular, this group of experts told a group of 16 children weighing say hello and nine were obese, all between 6 and 10 years of age, in both cases by measuring how fast their enzymes metabolize the caffeine and dextriometorfano , a key active ingredient in Robitussin cough suppressant, marketed by Wyeth.
As stated in the expert of Clinical Pharmacy, L’Aurelle Johnson, one of the authors of the study, obese children metabolize both substances “at a different pace” than other children, so that opens the way for further study this correlation of face-to redefine the doses of drugs for pediatric patients.
So far was already known that adults metabolize drugs differently, depending on your weight so that after this finding, its authors are committed to expand its research and analyzing the impact of obesity on the absorption, distribution and elimination of drugs.
In this way, Johnson said, “may better determine doses of each drug to maximize its effectiveness and at the same time reducing adverse effects, especially in the treatment of serious diseases like cancer.”